Single cell transcriptomics job at the Allen Institute 


(Bosiljka Tasic) #1

Scientist I job in Bosiljka Tasic’s group at the Allen Institute (to apply use the link below):

The Allen Institute for Brain Science, located in Seattle, Washington, is committed to understanding how the brain works and helping to unlock the mysteries of neurological diseases and disorders affecting millions worldwide.

The Allen Institute is seeking an exceptional candidate who will be part of a Seattle-based multidisciplinary team within the Cell Types Program. The successful candidate will participate in high-throughput single cell transcriptome data generation and analysis to support the effort funded by the newly awarded BRAIN grant from the NIH, which aims to define all cell types in the adult mouse brain. The candidate will be a Ph.D. graduate in life sciences or computational biology and will possess strong experimental and computational skills. She/he will collaborate with several other departments on the identification and classification of cell types in the mouse nervous system.

Job Responsibilities:
• Work within the Molecular Genetics team on experimental design, execution, and research associate training in order to generate large-scale single cell transcriptome datasets.
• Work with Modeling, Analysis and Theory team to timely and iteratively analyze single cell data from the internal single cell transcriptomics pipeline and facilitate generation of cell type taxonomy.
• Design and execute validation and follow-up experiments to place the transcriptomics results in the neurobiological context.
• Write and publish manuscripts, grant progress reports and grant applications.
• Present work internally and externally at conferences.
• Evaluate new single cell RNA-seq platforms and techniques.
• Work with Electrophysiology and Neuroanatomy teams to facilitate data organization and integration in an effort to create multimodal neuronal taxonomy.
Required Qualifications
• Ph.D. in life sciences or computational biology (e.g., Neuroscience, Genomics, Genetics, or related field).
• 2+ years of experimental experience in genomic data generation from primary tissues (rodent handling, dissection, single cell collection, molecular biology, and next generation sequencing).
• 2+ years of experience working in a rodent model system studying a neurobiological problem in vivo (e.g., developmental neurobiology, systems neurobiology).
• 2+ years of computational experience working with RNA-seq, ATAC-seq and/or ChIP-seq data, preferably at the single cell level.
• Ability to develop, test, implement, and share new experimental and computational tools quickly, in an iterative manner, after feedback from experimental, data production, and analysis teams.
• Proficiency in R and Linux shell scripting.

Desired Qualifications/Other:
• Experience with additional programming languages (Perl, Python, Matlab) preferred.
• Exceptional oral and written communication skills.
• Ability to work independently as well as part of a team to meet aggressive timelines in a collaborative environment.

It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.