Postdoctoral and research assistant/associate positions in Single Cell transcriptomics and metabolomics at the Moffitt Cancer Center

The Smalley Lab at the Moffitt Cancer Center in Tampa, Florida is recruiting postdocs, graduate students and research assistants. We have a variety of projects centered around single-cell analysis, including the study of tumor and TME heterogeneity in drug resistance and metastasis. We are committed to diversity and inclusion and we encourage people of all backgrounds to apply. For more information about our work and how to apply, please visit https://innasmalleylab.com or see the detailed posts below.

Postdoctoral Researchers

We are recruiting postdoctoral researchers interested in studying the role of metabolic heterogeneity and cross-talk in melanoma metastasis and drug resistance, as well as, developing novel single-cell and spatial transcriptomic and metabolomic techniques. These projects incorporate both basic and translational research, but overall aim to transform clinical care of late-stage melanoma patients.

Candidates will lead their project and collaborate closely with a team of immunologists, tumor biologists, bioinformaticians, mathematical modeling experts and clinicians at Moffitt Cancer Center (Tampa, FL) to conduct research in a highly collaborative environment. Ideal candidates have demonstrated expertise in signal transduction, metabolism, drug resistance, metastasis or single-cell analysis studies.

Position highlights
  • Studying the functionality of tumor heterogeneity, including metabolic symbiosis
  • Improving our understanding of interactions between the tumor and the TME
  • Developing cutting edge techniques for integrated single cell and spatial RNAseq and metabolomics
  • In addition to the research, the position will have a focus on career development including grant writing, scientific writing/presentation, mentorship of junior members of the lab, networking, and building collaborations.
Responsibilities
  • Working with patient specimens (acquisition, processing, preparation for analysis, biochemical screening), establishing and maintaining tumor cell cultures, cellular signaling and phenotypic assays, establishing in vivo models, metabolic assays, and proteomic analysis.
  • Providing intellectual input on steering the project
  • Developing novel technical approaches
  • Mentor graduate students and technicians
  • Compose manuscripts and postdoctoral fellowships, assist with grant applications
Credentials and qualifications
  • PhD in Cancer Biology, Molecular Biology, or a related field (required)
  • PhD awarded within the past year (preferred)
  • Strong written and oral communication skills and the ability to work independently and with collaborators.
How to apply

Candidates should e-mail the following documents to inna.smalley@moffitt.org

  1. A cover letter that describes their motivation to pursue this position, why they would be the perfect fit for these projects and summarizes past research accomplishments. They should also include a summary of what expectations/goals they have for this fellowship.

  2. A current CV with recent publications and contact information for three references.

Postdoctoral Researcher With Data Science Background

We are looking for candidates for the T32 Postdoctoral Fellowship in the Integrated Program in Cancer and Data Science (ICADS). In the Smalley Lab, the fellow would work on a project to develop novel analysis platforms for integrating and visualizing highly complex, cutting edge single-cell (1D and spatial) transcriptomics and metabolomics datasets. These analyses will allow us to better understand the tumor ecosystem and the functional role of intra-tumoral heterogeneity in metastasis and drug resistance. The fellow would be under joint supervision and mentorship of Dr. Brooke Fridley, Department Chair of Biostatistics and Bioinformatics as well as Dr. Inna Smalley, Department of Cancer Physiology.

The Department of Biostatistics and Bioinformatics at the H. Lee Moffitt Cancer Center is seeking a highly motivated, independent, and collaborative postdoctoral research fellow interested in conducting exciting inter-disciplinary research. The post-doctoral research fellow will collaborate with faculty members within the department on statistical genomics and bioinformatics methodology projects, along with, collaboration on collaborative cancer research projects. To learn more, check out this flyer.

The Ideal Candidate:
  • Strong written and oral communication skills and the ability to work independently and with collaborators.
  • Strong quantitative skills in the areas of biostatistics, statistical genomics and/or bioinformatics.
  • Programming experience in statistical program R and scripting languages such as Perl/Python on Unix/Linux systems.
  • Knowledge in biology or genetics is desired but not required.
Responsibilities:
  • Learn research methods that directly relate to the scientific projects with limited direction and supervision.
  • Collaborate on a variety of cancer and statistical/bioinformatics research projects
  • Develop scientific writing and presentation skills, including grant proposals, manuscript preparation, and formal seminars presented to the Moffitt scientific community and at national scientific meetings.
  • Work effectively within an interdisciplinary research team.
  • Provide intellectual input on steering the project
How To Apply:

Candidates should e-mail the following documents to: inna.smalley@moffitt.org

  1. A cover letter that describes their motivation to pursue this position, why they would be the perfect fit for these projects and summarizes past research accomplishments. They should also include a summary of what expectations/goals they have for this fellowship.

  2. A current CV with recent publications and contact information for three references.

Research Assistant/Associate

We are recruiting a Research Assistant/Associate of any level (I, II, or III) to work on projects related to the study of tumor heterogeneity in drug resistance and dissemination, as well as projects establishing in vitro and in vivo models of leptomeningeal metastasis. The candidate will be responsible for processing patient specimens, establishing cell lines and PDXs, maintaining cell cultures, and helping with various cell biology approaches and phenotypic assays. The candidate will also be responsible for lab management duties such as equipment maintenance, generation of common reagents, inventories, sample banking and purchase orders. Depending on interest and qualification, this position offers opportunities to further develop scientific skills such as the independent pursuit of research projects.

Position highlights
  • Learn advanced techniques in signal transduction, transcriptomic analysis and metabolomics assays
  • Lab management duties
  • Laboratory management experience
​Responsibilities
  • Cell culture
  • Tissue processing
  • Order laboratory supplies, maintain equipment, curate sample inventory, data presentations, provide high-quality figures for grants/papers.
  • Mentor rotation students and undergraduates
​Credentials and qualifications
  • BA or BS in molecular biology, biology or a related field (required)
How to apply

Candidates should e-mail the following to inna.smalley@moffitt.org

  1. A cover letter that describes their motivation to pursue this position, why they would be the perfect fit for this work and summarizes past research experience. They should also include a summary of what expectations/goals they have for this position.

  2. A current CV with recent publications and contact information for three references.

About Moffitt Cancer Center

Moffitt Cancer Center (Moffitt) is a free-standing NCI-designated Comprehensive Cancer Center and 501©(3) tax-exempt corporation located in Tampa, Florida. Moffitt opened in 1986 and is named in honor of H. Lee Moffitt, former Speaker of the House of Representatives of the State of Florida, who spearheaded the effort to create a cancer center whose sole mission is to “contribute to the prevention and cure of cancer.”

Research at Moffitt emphasizes the translation of basic and population science into improved diagnostic, preventive and therapeutic advances. Research program activities include both physicians and scientists who, collectively, comprise over 150 faculty and are focused into five distinct, but complementary, programs: Cancer Biology & Evolution; Immunology; Chemical Biology & Molecular Medicine; Cancer Epidemiology; and Health Outcomes & Behavior. Supporting these programs are 13 shared resources including, but not limited to, molecular sequencing, flow cytometry, analytic microscopy, molecular genomics, biostatistics, cancer informatics, proteomics, and chemical biology.

About Tampa, Florida

Tampa was recently named an “urban gem” and the “Best City in the Southeast” by Money magazine. It has been among the fastest growing cities in the US. Aside from the sunshine, beaches, and year- round outdoor recreation associated with the Gulf Coast of Florida, Tampa is a thriving metropolitan city with unique cultural attractions, low cost of living, and a high quality of life. We have four professional sports teams, and the beaches are less than an hour away. https://www.visittampabay.com/